學歷

1993/9~1999/7 中央大學統計所博士

1989/9~1993/7 中央大學數學系學士

經歷及現職

1. Associate Professor, August 2007 to present.
   Department of Public Health & Biostatistics Center , China Medical University, Taiwan.

2. Associate Research Scientist, June 2005 to August 2007.
   Institute of Statistical Science, Academia Sinica, Taiwan.

3. Visiting Research Assistant Professor, September 2004 to May 2005. Biostatistics and Bioinformatics Unit, Comprehensive Cancer Center, UAB.

4. Postdoctoral Fellow, February 2002 to September 2004.
   Dr. James J. Chen, Division of Biometry and Risk Assessment, NCTR, FDA.

5. Postdoctoral Fellow, March 2001 to December 2001.
   Professor Ueng-Cheng Yang, Institute of Biochemistry, National Yang-Ming University, Taiwan.
   　

                                                                                                    Update: 2007/07/31

1. Chen, J.J., Lee, T., Delongchamp, R.R., Chen, T., and Tsai, C.A. (2007). Significance analysis of groups of genes in expression profiling. Bioinformatics, to appear. (SCI, IF=4.894)

2. Tsai, C.A. and Chen, J.J. (2007). Kernel Estimation for Adjusted p-values in Multiple Testing. Computational Statistics & Data Analysis, 51, 3885-3897. (SCI, IF=0.733)

3. Tsai, C.A., Chen, D.T., Chen, J.J., Balch, C.M., Thompson, J.F., and Soong, S.J. (2007). An integrated tree-based classification approach to prognostic grouping with application to localized melanoma patients. Journal of Biopharmaceutical statistics, 17(3), 445-460. (SCI)

4. Chen, J.J., Tsai, C.A., Tzeng, S.L. and Chen, C.C. (2007). Gene selection with multiple ordering criteria. BMC Bioinformatics, 8:74. (SCI, IF=4.96)

5. Hsueh, H.M. and Tsai, C.A. (2006). Controlling the false discovery rate for the SAM method. Journal of the Chinese Statistical Association, 44, 364-381.

6. Hsueh, H.M., Tsai, C.A., and Chen, J.J. (2006). Incorporating the number of true null hypotheses to improve power in multiple testing: application to gene microarray data. Journal of Statistical Computation and Simulation, to appear. (SCI, IF=0.284)

7. Chen, J.J., Wang, S.J., Tsai, C.A., and Lin, C.J. (2006). Selection of Differentially Expressed Genes in Microarray Data Analysis. The Pharmacogenomics Journal, 1-9. (SCI, IF=3.989)

8. Young, J.F., Tsai, C.A., Chen, J.J., Latendresse, J.R. and Kodell, R.L. (2006). Database Composition Can Affect the Structure-Activity Relationship Prediction. Journal of Toxicol­ogy and Environmental Health, Part A, 69, 1527-1540. (SCI, IF=1.892)

9. Chen, J.J., Tsai, C.A., Moon, H., Ahn, H., Young, J.F., and Chen, C.H. (2006). Decision Threshold Adjustment in Class Prediction. SAR and QSAR in Environmental Research, 17(3),337-352. (SCI, IF=1.753)

10. Chen, J.J., Tsai, C.A., Young, J.F. and Kodell, R.L. (2005). Classification Ensembles for Unbalanced Class Sizes in Predictive Toxicology. SAR and QSAR in Environmental Research, 16(6), 517-529. (SCI, IF=1.753)

11. Tsai, C.A., Wang, S.J., Chen, D.T., and Chen, J.J. (2005). Sample Size for Gene Expression Microarray Experiments. Bioinformatics, 21(8), 1502-1508. (SCI, IF=6.019)

12. Akerman, G.S., Rosenzweig, B.A., Domon, O.E., Tsai, C.A., McGarrity, L.J., Bishop, M., MacGregor, J.T., Sistare, F.D., Chen, J.J., and Morris, S.M. (2005). Alterations in the gene expression profiles and the DNA damage response in ionizing radiation-exposed TK6 cells. Environmental and Molecular Mutagenesis, 45, 188-205. (SCI, IF=2.043)

13. Tsai, C.A., Lee, T.C., Ho, I.C., Yang, U.C., Chen, C.H., and Chen, J.J. (2005). Multi-class Clustering and Prediction in the Analysis of Microarray Data. Mathematical Biosciences, 193, 79-100. (SCI, IF=1.358)

14. Tsai, C.A. and Chen, D.T. (2005). Quality assessment of gene expression data. In: Pr'oceed­ings of Emerging Information Technology Conference, 2005. 15-16 A ug, 2005.

15. Tsai, C.A., and Chen, J.J. (2004). Significance Analysis of ROC Indices for Comparing Diagnostic Markers: Applications to Gene Microarray Data. Journal of Biopharmacetdical statistics, 14(4),985-1003.

16. Tsai, C.A., Chen, C.H., Lee, T.C., Ho, I.C., Yang, U.C., and Chen, J.J. (2004). Gene Se­lection for Sample Classification in Microarray Experiments. DNA and Cell Biology, 23, 607-614. (SCI,IF=1.794)

17. Tsai, C.A., Hsueh, H-M, and Chen, J.J. (2004). A generalized additive model for microarray gene expression data analysis. Journal of Biopharmaceutical statistics, 14, 553-573.

18. Chen, J.J., Delongchamp, RR, Tsai, C.A., Hsueh, H.-M., Sistare, F.D., Thompson, KL., Desai, V.G., and Fuscoe, J.C. (2004). Analysis of Variance Components in Gene Expression Data. Bioinformatics, 20, 1436-1446. (SCI,IF=6.019)

19. Akerman, G.S., Rosenzweig, B.A., Domon, O.E., McGarrity, L.J., Blankenship, L.R, Tsai, C.A., Culp, S.J., MacGregor, J.T., Sistare, F.D., Chen, J.J., and Morris, S.M. (2004). Gene Ex­pression Profiles and Genetic Damage in Benzo(a)Pyrene Diol Epoxide-Exposed TK6 Cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 549(1-2):43-64. (SCI, IF=3.340)

20. Tsai, C.A., Hsueh, H.-M., and Chen, J.J. (2003). Estimation of false discovery rates in multiple testing: application to gene microarray data. Biometrics, 59, 1071-1081. (SCI, IF=1.602)

21. Tsai, C.A., Chen, YJ., and Chen, J.J. (2003). Testing for Differentially Expressed Genes for Microarray Data. Nucleic Acid Research, 31(9), e52. (SCI,IF=7.552)

22. Fan, T.H. and Tsai, C.A. (1999). A Bayesian Method in Determining the Order of a Finite State Markov Chain. Communication in Statistics: Theory and Method, 28(7), 1711-1730. (SCI, IF=0.209)

23. Fan, T.H. and Tsai, C.A. (1999). Intrinsic Bayes factor for change-point analysis of a Gaussian model. Dissertation.